Cadenza CD-C18 3µm 50x2.0mm (ODS end-capped)

The Cadenza CD-C18 HPLC column 50x2.0mm, 3µm, bears an octadecyl modification (ODS, RP-18, C18) with polymeric methyl endcapping on fully porous, high-purity silica with 12 nm pores and is assigned to USP class L1. The polymeric endcapping renders the surface resistant to acids and bases and permits an operating range of pH 1.5 to 9. Typical applications are 25-hydroxyvitamin D in serum, omega-3 and omega-6 fatty acids and their ethyl esters, carotenes, fat-soluble vitamins, flavonoids in grapefruit juice, endosulfan isomers and peptide mapping.

Features and Benefits

• Fully porous, high-purity silica
• Five end-capping and pore designs
• Polymer end-capping for acid and alkali resistance
• High plate number
• Compression-resistant and metal-free versions available

Additional Notes

Cadenza is a family consisting exclusively of octadecyl phases. All phases use the same fully porous, high-purity silica support and the same ligand chemistry, but differ in their end-capping design and pore size. This results in significantly different selectivities, meaning the phases are not considered interchangeable during method transfers. Each phase is also available in a pressure-resistant version rated for 500 bar, a version rated for 1000 bar, and a metal-free version with a PEEK-coated fluid path, each with identical packing material. The metal-free variant is intended for coordinating and phosphorylated compounds whose peak shape is adversely affected by stainless steel.

Legal Information

Cadenza is a product line of Imtakt Corporation, Kyoto, Japan. The product and phase names mentioned are part of the manufacturer's chromatography portfolio.