Halo Peptide ES-CN 160Å 2.7µm 100x3.0mm CoreShell Column 1 pc

The HALO 160 Å ES-CN HPLC column 100x3.0mm, 2.7µm, is a cyano-phase column based on core-shell particles that can be used in both reversed-phase and normal-phase chromatography. The CN group enables dipole-dipole and π-π interactions, and the hydrophobic linker also allows for weak hydrophobic interactions. In addition, the HALO 160 Å ES-CN has isopropyl side chains attached directly to the silane, enabling pH stability down to 1. These different interactions result in a selectivity profile distinct from that of C18 phases. The 160 Å pore size also makes the HALO 160 Å ES-CN ideally suited for the analysis of peptides, such as tryptic digests, post-translational modifications (PTMs), or polypeptides.

Features and Benefits

• Core-shell particles for fast methods
• UHPLC performance on HPLC systems
• High efficiency
• Low backpressure

Additional Notes

The HALO Bioclass series is based on a core-shell material. This means that the particles have a non-porous core and a porous shell. This allows for high efficiency while maintaining low backpressure. As a result, UHPLC performance is possible using a standard HPLC system. Compared to the HALO series, the HALO Bioclass series features larger pores (160 Å, 400 Å, and 1,000 Å). This allows biological samples—ranging from small peptides to proteins and antibodies—to be analyzed using core-shell technology. The service life can be extended by using appropriate precolumn cartridges.

Legal Notices

HALO is a registered trademark of the manufacturer Advanced Materials Technology, Inc., Wilmington, USA.