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The Ultra Flash C18 flash cartridge is packed with irregularly shaped octadecyl silica and operates as a reversed phase. Octadecyl is used interchangeably as ODS, RP-18 or C18. Separation is via hydrophobic interaction, so polar and non‑polar components of a crude product can be separated from one another with mixtures of water and methanol or acetonitrile. Thus the cartridge captures substances that are too polar or too water‑soluble for normal phase, for example natural products and products from aqueous extracts. The USP class L1 is assigned, and the coarse particles maintain a high flow and short separation time.
Ultra Flash encompasses UCT’s flash cartridges. Flash chromatography falls between open-column chromatography and preparative HPLC, as it uses coarse particles, low pressure, and short run times, thereby separating quantities in the gram range. Therefore, when purifying a crude product from a synthesis, the cartridge is selected not based on length and diameter, but on the filling capacity, which is determined by the amount of substance to be loaded. The same chemistry is available across the entire range from a few grams to over one kilogram, allowing a separation developed on a small scale to be scaled up to a larger scale without changing the material. The series is divided into three model lines, which differ in their cartridge housings and connections and can be identified by their part numbers. Two factors determine which model is suitable: the connection of the existing Flash system and the maximum amount of substance to be processed. Ultra Flash I is the only model that also covers the range above three hundred grams and extends into the kilogram range, making it the choice for large batches. Ultra Flash II covers the range up to three hundred grams. Ultra Flash III, with an iLOK connection, covers the same range but offers the finest gradation of filling volumes, allowing for the most precise adjustment to the sample quantity. This series also includes an empty cartridge into which a poorly soluble sample can be loaded as a solid before it is fed into the separation column.
Ultra Flash is a trademark of UCT, Inc., Bristol, Pennsylvania. The product and phase names mentioned are part of the manufacturer's chromatography portfolio.
| Brand | Ultra Flash |
|---|---|
| Product Type | Flash Column |
| Chemistry | C18 (RP-18, ODS, Octadecyl) |
| Chemistry Producers Term | C18 |
| USP Class | L1 |
| Country of Origin | United States of America (USA) |
| Mode of Separation | Reversed Phase Chromatography (RP) |