RPSep PRX-1 Column, SS 250 mm x 4.6 mm

The RPSep PRX-1 HPLC column 250x4.6mm, 5µm, based on a PS/DVB polymer for reverse-phase chromatography. RPSep PRX-1 offers robust polymer selectivity without a conventional silica surface and is suitable for methods requiring a very wide pH range. Typical applications include small organic molecules, peptides, pharmaceutical samples, biological matrices and robust RP separations under demanding pH conditions.

Features and Benefits

• PS/DVB-based polymer reverse-phase columns
• High pH and temperature stability depending on modification
• Non-porous and highly efficient phases for fast RP separations
• C18, PFP, and non-alkylated polymer selectivities available

Additional Information

The RPSep series is primarily based on polystyrene-divinylbenzene polymers and thus offers an alternative to silica-based reverse-phase columns. The polymer backbone enables high chemical robustness, broad pH stability, and a narrow particle size distribution for efficient separations. Depending on the modification, hydrophobic, aromatic, or fluorinated interactions are created. As a result, RPSep is suitable for small molecules, peptides, aromatic compounds, and LC-MS-related methods that require robust RP selectivity.

Legal Notices

RPSep is a registered trademark of the manufacturer Concise Separations, San Jose, USA.