HILICpak VN-50 10E, 10.0 x 250 mm, preparative HPLC column

The HILICpak VN-50 HPLC column 250x10mm, 5µm, based on a neutral diol modification on polyvinyl alcohol. HILICpak VN-50 provides hydrophilic retention without permanently bound ionic groups and is suitable, among other things, for oligonucleotides, oligosaccharides and other polar biomolecules. The 1-mm ID version uses pressure-stable double-walled hardware made of stainless steel and PEEK, while the stationary phase remains unchanged.

Features and Benefits

• Polymer-based HILIC phases
• Neutral and ionic selectivities
• High stability in aqueous-organic eluents
• Suitable for LC-MS and aerosol detectors
• Focus on highly polar analytes

Additional Notes

HILICpak uses porous polyvinyl alcohol particles as a hydrophilic backbone. The PVA matrix carries amino, diol, carboxyl, or quaternary ammonium groups, thereby enabling HILIC separations with neutral, anionic, or cationic secondary interactions. Unlike silica-based amino phases, the polymer material is less susceptible to hydrolytic aging. The choice of modification depends on the charge, hydrogen-bonding ability, and polarity of the target analytes.

Legal Information

HILICpak is a registered trademark of the manufacturer, Resonac Corporation, Tokyo, Japan.