IEC QA-5025 300x50mm Ion Exchange Preparative Column

The Shodex IEC QA-5025 preparative HPLC column300x50mm, 37µm, utilises a large-pore polyhydroxymethacrylate gel with quaternary ammonium groups as a strong anion exchanger. The large-scale, coarse-particle packing bed is designed for very high sample loadings and the transfer of established QA separations to the larger preparative scale. Shodex IEC QA-5025 is suitable for the recovery and purification of proteins, peptides, nucleic acids and other negatively charged biomolecules.

Features and Benefits

• Strong and weak ion exchangers
• Anion and cation phases
• Large-pore materials for biomolecules
• Non-porous option for rapid separations
• Hydrophilic polymer backbones

Additional Notes

The IEX Series combines polyhydroxymethacrylate, polyvinyl alcohol, and styrene-divinylbenzene frameworks. Quaternary ammonium and sulfopropyl groups act as strong ion exchangers, while DEAE and carboxymethyl groups act as weak ion exchangers. Large-pore packing improves access for proteins and nucleic acids, while nonporous particles offer particularly short transport paths. The choice of phase depends on net charge, isoelectric point, molecular size, and the desired elution strategy.

Legal Information

Shodex is a registered trademark of Resonac Corporation, Tokyo, Japan. The IEX Series is a product line within the Shodex portfolio.