IEC PIKESS SP-2B 50x2.0mm Ion exchange

The Shodex PIKESS SP-2B UHPLC column 50x2.0mm, 2.5µm, combines non-porous polyhydroxymethacrylate particles with sulfopropyl groups as a strong cation exchanger. The pressure-stable semi-micro format allows very short gradients, high efficiency and reduced eluent consumption. Shodex PIKESS SP-2B is suitable for fast separations of proteins, peptides, antibody variants and other cationic biomolecules.

Features and Benefits

• Strong and weak ion exchangers
• Anion and cation phases
• Large-pore materials for biomolecules
• Non-porous option for rapid separations
• Hydrophilic polymer backbones

Additional Notes

The IEX Series combines polyhydroxymethacrylate, polyvinyl alcohol, and styrene-divinylbenzene frameworks. Quaternary ammonium and sulfopropyl groups act as strong ion exchangers, while DEAE and carboxymethyl groups act as weak ion exchangers. Large-pore packing improves access for proteins and nucleic acids, while nonporous particles offer particularly short transport paths. The choice of phase depends on net charge, isoelectric point, molecular size, and the desired elution strategy.

Legal Information

Shodex is a registered trademark of Resonac Corporation, Tokyo, Japan. The IEX Series is a product line within the Shodex portfolio.