IEC SP-FT 4A, 4.6 x 10 mm, HPLC column

The Shodex IEC SP-FT 4A HPLC column 10x4.6mm, 2.7µm, contains sulfo­propyl groups as a strong cation exchanger on non-porous polymer particles. The absence of internal pores shortens diffusion paths and enables very fast charge variant separations. The small particle size increases efficiency in short column formats. Typical application areas of Shodex IEC SP-FT 4A are rapid protein and antibody analyses as well as high-throughput methods.

Features and Benefits

• Strong and weak ion exchangers
• Anion and cation phases
• Large-pore materials for biomolecules
• Non-porous option for rapid separations
• Hydrophilic polymer backbones

Additional Notes

The IEX Series combines polyhydroxymethacrylate, polyvinyl alcohol, and styrene-divinylbenzene frameworks. Quaternary ammonium and sulfopropyl groups act as strong ion exchangers, while DEAE and carboxymethyl groups act as weak ion exchangers. Large-pore packing improves access for proteins and nucleic acids, while nonporous particles offer particularly short transport paths. The choice of phase depends on net charge, isoelectric point, molecular size, and the desired elution strategy.

Legal Information

Shodex is a registered trademark of Resonac Corporation, Tokyo, Japan. The IEX Series is a product line within the Shodex portfolio.