UltraCore SuperC18 UHPLC GRDS 4.0-4.

The Avantor ACE UltraCore SuperC18Guard cartridges 4.6mm are used for column protection of Avantor ACE UltraCore SuperC18 HPLC and UHPLC columns with an internal diameter of 4.6mm. They protect the analytical solid-core column from matrix components and particulate contaminants. For reproducible separations the guard cartridge should be combined with the same UltraCore modification as the main column. The direct holder H0011 serves as the guard holder.

Features and Benefits

• Silica-based solid-core and core-shell particles for high efficiency
• Fast separations at moderate backpressure
• Ultra-inert surface chemistry for reproducible peak shapes
• Extended-pH phases for robust method development
• Variants for small molecules as well as BIO phases for proteins and peptides

Additional Notes

The Avantor ACE UltraCore series uses spherical silica particles with a non-porous core and a porous outer layer. This solid-core architecture reduces diffusion paths and enables high separation efficiencies while maintaining low backpressure. The surface of the silica particles is designed to minimize unwanted silanol activity, which promotes symmetrical peaks and robust retention times. By using compatible UltraCore guard cartridges, the analytical column can be protected from matrix interference without altering the selective chemistry of the main column.

Legal Notices

Avantor ACE is a registered trademark of the manufacturer Avantor, Inc., Radnor, USA.