Carbo Sep CHO-411 Oligosaccharide, SS 300 mm x 7.8 mm

The CarboSep CHO 411 HPLC column (300 × 7.8 mm, 20 µm) is a sodium form with 4 % cross-linking, designed for ligand-exchange chromatography of carbohydrates. Due to its low degree of cross-linking, the CarboSep CHO 411 has a comparatively open-pored polymer resin and is particularly suitable for mono-, di- and higher oligosaccharides. Typical applications include sugar profiling in foodstuffs, beverages, fermentation samples and hydrolysed carbohydrate matrices.

Features and Benefits

• Polymer-based ligand-exchange resins for carbohydrates
• Various counterions, such as Na+, Ca2+, Pb2+, and K+, for targeted selectivity
• Cross-linking degrees of 4, 6, 7, and 8% to adjust porosity, resolution, and robustness
• Suitable for monosaccharides, disaccharides, and oligosaccharides

Additional Notes

The CarboSep series uses polymer-based packing materials with defined counterions and degrees of cross-linking. Unlike conventional silica phases, retention is not based on hydrophobic surface interactions, but rather on ligand exchange and size- or structure-dependent interactions between the carbohydrates and the polymer resin. This allows sugars, sugar alcohols, and oligosaccharides to be separated in highly aqueous eluents. The polymer backbone used is designed for routine applications in carbohydrate analysis; compatible CarboSep pre-column cartridges help keep matrix components out of the main column.

Legal Notices

CarboSep is a registered trademark of the manufacturer Concise Separations, San Jose, USA.