Sumipax C8 Z-CLUE 3µm 250x4,6mm

The Sumipax C8 Z-CLUE HPLC column 250x4.6mm, 3µm, carries an octyl modification (RP-8, C8) and is assigned to USP class L7. The same metal-reduced silica gel with 130 Å pores is used as the support as in the octadecyl range Sumipax ODS Z-CLUE, and the endcapping is highly controlled. The shorter alkyl chain reduces retention compared with the octadecyl variant and thus shortens analysis time. Anyone with a method on the octadecyl phase who needs an earlier-eluting run will find here the same support base with weaker hydrophobicity. The operating range extends from pH 1.5 to 9.0, and the column is available in 3 and 5 µm with internal diameters of 2.0 to 4.6 mm.

Features and Benefits

• Silica gel with very low metal content
• Less tailing with complexing agents
• Eight octadecyl phases with graded selectivity
• Silica gel, core-shell silica, and porous glass
• Identical chemistry across multiple particle sizes
• Inline glass filter instead of a pre-column

Additional Notes

What makes Sumipax unique is the silica gel itself, as it is exceptionally low in metals. Traces of aluminum, iron, titanium, zirconium, and calcium in the particles act as active sites that bind complex-forming substances, thereby causing tailing and poor recovery. Sumipax limits these five metals to a maximum of 10 ppm per element and lists this value as a guaranteed specification rather than a marketing claim; for the Z-CLUE series, the limit is even 1 ppm. For phosphates, chelating agents, tetracyclines, and similarly sensitive substances, this is the practical difference compared to other brands. Secondly, the octadecyl group—which appears eight times—is noteworthy; however, the eight series are not duplicates but rather a deliberate gradation based on pore size, packing density, pH range, and base material. Thirdly, within the brand, there are three different base materials for the particles: fully porous silica gel, core-shell silica, and porous glass. Regarding the abbreviations in the product names: MS stands for an inner diameter of 2.0 mm for mass spectrometric coupling, EC for the solvent-saving version with a 3.0 mm diameter, and SLP for the low-pressure fine-particle version of the D series. The brand does not include chiral phases.

Legal Information

Sumipax is a product line of Sumika Chemical Analysis Service, Ltd., Osaka, Japan, and Sumipax is a trademark registered in Japan. The product and phase names mentioned are part of the manufacturer’s chromatography portfolio.