BioBasic 18 5µm 150x1mm Column

The BioBasic 18 HPLC column 150x1.0mm, 5µm, is based on wide-pore 300Å silica with an endcapped octadecyl phase (other designations: ODS, RP-18, C18). The reversed phase provides strong hydrophobic retention with good pore access for biomolecules. The large pore supports efficient mass transport and reproducible gradients. BioBasic 18 is used particularly for peptides, proteins, oligonucleotides and biomarkers.

Features and Benefits

• Wide-pore silica phases for biomolecules
• Reverse-phase, ion exchange, and size exclusion
• Graded hydrophobicity from C18 to C4
• SEC pore sizes for different molecular weights
• Analytical and biocompatible applications

Additional Information

BioBasic includes large-pore silica-based phases for proteins, peptides, oligonucleotides, and other biomolecules. Alkyl, phenyl, and cyano surfaces cover reverse-phase chromatography; AX and SCX cover charge separation; and SEC 60 through SEC 1000 cover various hydrodynamic size ranges. In SEC, pore size and the calibration-dependent fractionation range are critical; in ion exchange, pH and ionic strength determine binding.

Legal Information

Thermo Scientific is a brand name of Thermo Fisher Scientific Inc. BioBasic refers to a product line within the Thermo Scientific chromatography portfolio.