BIOshell 120 Oligo C18 2.7 µm 150x2.1mm

The BIOshell Oligo C18 HPLC-/UHPLC column 150x2.1mm, 2.7µm, utilises a C18-based surface with a specialised modification for oligonucleotides. The BIOshell Oligo C18 is employed in ion-pair reversed-phase methods and is tailored to oligonucleotides as well as nucleic acid fragments. Applications of the BIOshell Oligo C18 include oligonucleotide purity, siRNA, antisense oligos, sequence variants and LC-MS analytics.

Features and Benefits

• Fused-Core Bio-LC particles
• Large pores for biomolecules
• Suitable for proteins, peptides, glycans, and oligos
• LC-MS-compatible applications
• High efficiency in bioseparations

Additional Information

BIOshell columns use fused-core particles designed for biomolecules. Depending on the phase, larger pores are available for intact proteins and antibodies, medium-sized pores for peptides and oligonucleotides, and HILIC-like surfaces for glycans. The short diffusion path of the core-shell particles promotes narrow peaks, while the surface chemistry is optimized for typical bio-LC applications. As a result, BIOshell can be used for fast, sensitive, and MS-compatible bioanalytics.

Legal Information

BIOshell is a registered trademark of the manufacturer Merck KGaA, Darmstadt, Germany.