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BIOshell™ A400 Protein C18 Column, L x I.D. 2 cm x 4.6 mm, 3.4 µm particle size
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Product Description
The BIOshell A400 Protein C18 HPLC-/UHPLC column 20x4.6mm, 3.4µm, employs a C18 modification on 400Å pores. The BIOshell A400 Protein C18 provides stronger retention than the C4 variant and is suitable for more hydrophobic proteins or peptide mixtures. Typical applications of the BIOshell A400 Protein C18 are protein digestion, protein fragments, peptide mapping and bioanalysis.
Features and Benefits
- Fused-Core Bio-LC particles
- Large pores for biomolecules
- Suitable for proteins, peptides, glycans, and oligos
- LC-MS-compatible applications
- High efficiency in bioseparations
Additional Information
BIOshell columns use fused-core particles designed for biomolecules. Depending on the phase, larger pores are available for intact proteins and antibodies, medium-sized pores for peptides and oligonucleotides, and HILIC-like surfaces for glycans. The short diffusion path of the core-shell particles promotes narrow peaks, while the surface chemistry is optimized for typical bio-LC applications. As a result, BIOshell can be used for fast, sensitive, and MS-compatible bioanalytics.
Legal Information
BIOshell is a registered trademark of the manufacturer Merck KGaA, Darmstadt, Germany.
Product Specification
| Brand | BIOshell |
|---|---|
| Product Type | CoreShell Column |
| Length | 20 mm |
| Internal Diameter | 4.6 mm |
| Particle Size | 3.4 µm |
| Chemistry | C18 (RP-18, ODS, Octadecyl) |
| Chemistry Producers Term | A400 Protein C18 |
| Pore Size | 400 Å |
| USP Class | L1 |
| Bet Surface Area [m2/g] | 90.0 |
| Endcapping | endcapped |
| Country of Origin | Germany |
| Column Type | Analytical Column |
| Hardware Material | Stainless Steel |
| Hardware Type | Ready-to-use Column |
| pH Minimum | 1.0 |
| pH Maximum | 9.0 |
| Temperature Maximum [°C] | 90 |
| Mode of Separation | Reversed Phase Chromatography (RP) |
| Technology | HPLC |
| Matrix | Silica |
| Particle Morphology | spherical, solid core, porous shell |
| Pressure Stability | 600 bar |
