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BIOshell™ lgG, C4 HPLC Column, 2.7 µm particle size, L x I.D. 3 cm x 4.6 mm
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Product Description
The BIOshell IgG 1000 Å C4 HPLC/UHPLC column 30x4.6mm, 2.7µm, features a C4 modification on fused-core particles with a very large pore structure. The BIOshell IgG 1000 Å C4 is designed for intact proteins, antibodies and large protein variants. Typical applications of the BIOshell IgG 1000 Å C4 are antibody characterisation, intact mAbs, protein variants and RP bio-LC methods with milder retention than C18.
Features and Benefits
- Fused-Core Bio-LC particles
- Large pores for biomolecules
- Suitable for proteins, peptides, glycans, and oligos
- LC-MS-compatible applications
- High efficiency in bioseparations
Additional Information
BIOshell columns use fused-core particles designed for biomolecules. Depending on the phase, larger pores are available for intact proteins and antibodies, medium-sized pores for peptides and oligonucleotides, and HILIC-like surfaces for glycans. The short diffusion path of the core-shell particles promotes narrow peaks, while the surface chemistry is optimized for typical bio-LC applications. As a result, BIOshell can be used for fast, sensitive, and MS-compatible bioanalytics.
Legal Information
BIOshell is a registered trademark of the manufacturer Merck KGaA, Darmstadt, Germany.
Product Specification
| Brand | BIOshell |
|---|---|
| Product Type | CoreShell Column |
| Length | 30 mm |
| Internal Diameter | 4.6 mm |
| Particle Size | 2.7 µm |
| Chemistry | C4 |
| Chemistry Producers Term | IgG C4 |
| Pore Size | 1.000 Å (10e3 Å) |
| USP Class | L26 |
| Carbon Load | 0.6 % |
| Bet Surface Area [m2/g] | 22.0 |
| Endcapping | endcapped |
| Country of Origin | Germany |
| Column Type | Analytical Column |
| Hardware Material | Stainless Steel |
| Hardware Type | Ready-to-use Column |
| pH Minimum | 2.0 |
| pH Maximum | 9.0 |
| Temperature Maximum [°C] | 90 |
| Mode of Separation | Reversed Phase Chromatography (RP) |
| Technology | HPLC |
| Matrix | Silica |
| Particle Morphology | spherical, solid core, porous shell |
| Pressure Stability | 1000 bar |
