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The BIOshell IgG 1000 Å C18 HPLC/UHPLC column 30x3.0mm, 2.7µm, is based on an octadecyl phase (also known as ODS, RP-18, C18) with 1000 Å pores. The BIOshell IgG 1000 Å C18 offers stronger hydrophobic retention of large biomolecules. The BIOshell IgG 1000 Å C18 is used for antibodies, hydrophobic protein variants, intact proteins and biopharmaceutical RP methods.
BIOshell columns use fused-core particles designed for biomolecules. Depending on the phase, larger pores are available for intact proteins and antibodies, medium-sized pores for peptides and oligonucleotides, and HILIC-like surfaces for glycans. The short diffusion path of the core-shell particles promotes narrow peaks, while the surface chemistry is optimized for typical bio-LC applications. As a result, BIOshell can be used for fast, sensitive, and MS-compatible bioanalytics.
BIOshell is a registered trademark of the manufacturer Merck KGaA, Darmstadt, Germany.
| Brand | BIOshell |
|---|---|
| Product Type | CoreShell Column |
| Length | 30 mm |
| Internal Diameter | 3.0 mm |
| Particle Size | 2.7 µm |
| Chemistry | C18 (RP-18, ODS, Octadecyl) |
| Chemistry Producers Term | IgG C18 |
| Pore Size | 1.000 Å (10e3 Å) |
| USP Class | L1 |
| Carbon Load | 1.4 % |
| Bet Surface Area [m2/g] | 22.0 |
| Endcapping | endcapped |
| Country of Origin | Germany |
| Column Type | Analytical Column |
| Hardware Material | Stainless Steel |
| Hardware Type | Ready-to-use Column |
| pH Minimum | 1.0 |
| pH Maximum | 8.0 |
| Mode of Separation | Reversed Phase Chromatography (RP) |
| Technology | HPLC |
| Matrix | Silica |
| Particle Morphology | spherical, solid core, porous shell |
| Pressure Stability | 600 bar |