BIOshell™ IgG 1000 Å Diphenyl, 2.7 µm HPLC Column, L x I.D. 15 cm x 3 mm

The BIOshell IgG 1000 Å Diphenyl HPLC/UHPLC column 150x3.0mm, 2.7µm, uses a diphenyl modification with very large pore structure. The BIOshell IgG 1000 Å Diphenyl combines hydrophobic and aromatic interactions and can separate antibody variants differently to alkyl phases. Typical applications of the BIOshell IgG 1000 Å Diphenyl are intact mAbs, ADCs, protein variants and methods with additional aromatic selectivity.

Features and Benefits

• Fused-Core Bio-LC particles
• Large pores for biomolecules
• Suitable for proteins, peptides, glycans, and oligos
• LC-MS-compatible applications
• High efficiency in bioseparations

Additional Information

BIOshell columns use fused-core particles designed for biomolecules. Depending on the phase, larger pores are available for intact proteins and antibodies, medium-sized pores for peptides and oligonucleotides, and HILIC-like surfaces for glycans. The short diffusion path of the core-shell particles promotes narrow peaks, while the surface chemistry is optimized for typical bio-LC applications. As a result, BIOshell can be used for fast, sensitive, and MS-compatible bioanalytics.

Legal Information

BIOshell is a registered trademark of the manufacturer Merck KGaA, Darmstadt, Germany.