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The BIOshell Glycan HPLC/UHPLC column 150x4.6mm, 2.7µm, has a polar pentahydroxy-like surface for HILIC separations. The BIOshell Glycan is designed for labelled and native glycans that show little retention in RP methods. Typical applications of the BIOshell Glycan are N-glycan profiling, biopharmaceutical glycan analysis, 2-AB- or other fluorescently labelled glycans and LC-MS methods.
BIOshell columns use fused-core particles designed for biomolecules. Depending on the phase, larger pores are available for intact proteins and antibodies, medium-sized pores for peptides and oligonucleotides, and HILIC-like surfaces for glycans. The short diffusion path of the core-shell particles promotes narrow peaks, while the surface chemistry is optimized for typical bio-LC applications. As a result, BIOshell can be used for fast, sensitive, and MS-compatible bioanalytics.
BIOshell is a registered trademark of the manufacturer Merck KGaA, Darmstadt, Germany.
| Brand | BIOshell |
|---|---|
| Product Type | CoreShell Column |
| Length | 150 mm |
| Internal Diameter | 4.6 mm |
| Particle Size | 2.7 µm |
| Chemistry | Glycan |
| Chemistry Producers Term | Glycan |
| Pore Size | 90 Å |
| USP Class | L95 |
| Bet Surface Area [m2/g] | 135.0 |
| Endcapping | non endcapped |
| Country of Origin | Germany |
| Column Type | Analytical Column |
| Hardware Material | Stainless Steel |
| Hardware Type | Ready-to-use Column |
| pH Minimum | 2.0 |
| pH Maximum | 9.0 |
| Temperature Maximum [°C] | 60 |
| Mode of Separation | Hydrophilic Interaction Chromatography (HILIC) |
| Technology | HPLC |
| Matrix | Silica |
| Particle Morphology | spherical, solid core, porous shell |
| Pressure Stability | 1000 bar |