BIOshell A160 Peptide PCS-C18, 2.7 µm HPLC Guard Cartridge, L × I.D. 5 mm × 4.6 mm

The BIOshell A160 Peptide PCS-C18 HPLC/UHPLC column 5x4.6mm, 2.7µm, combines an octadecyl modification (other designations: ODS, RP-18, C18) with a positively charged surface chemistry on 160 Å fused-core particles. The BIOshell A160 Peptide PCS-C18 particularly improves peak shape and loadability for basic peptides and allows lower concentrations of mobile phase additives. Typical applications are peptide mapping, tryptic digests, post-translationally modified peptides, polypeptides and small proteins up to about 25 kDa as well as LC–MS-compatible biopharmaceutical analysis.

Features and Benefits

• Fused-Core Bio-LC particles
• Large pores for biomolecules
• Suitable for proteins, peptides, glycans, and oligos
• LC-MS-compatible applications
• High efficiency in bioseparations

Additional Information

BIOshell columns use fused-core particles designed for biomolecules. Depending on the phase, larger pores are available for intact proteins and antibodies, medium-sized pores for peptides and oligonucleotides, and HILIC-like surfaces for glycans. The short diffusion path of the core-shell particles promotes narrow peaks, while the surface chemistry is optimized for typical bio-LC applications. As a result, BIOshell can be used for fast, sensitive, and MS-compatible bioanalytics.

Legal Information

BIOshell is a registered trademark of the manufacturer Merck KGaA, Darmstadt, Germany.