XTerra MS C18 OBD Prep Column, 125Å, 2.5 µm, 10 mm X 50 mm, 1/pkg

The Waters XTerra MS C18 HPLC/UHPLC column 50x10mm, 2.5µm, is based on an octadecylsilyl phase (other designations: ODS, RP-18, C18) on Hybrid-Particle-Technology (HPT) particles and is designed for reversed-phase chromatography. The MS variant is designed for low bleed, good peak shape for basic compounds and LC–MS compatibility. In practice, Waters XTerra MS C18 is suitable, for example, for drug discovery analysis, LC–MS workflows, high-pH methods and active pharmaceutical ingredient screening.

Performance Characteristics and Benefits

• Organic-inorganic hybrid particles
• Extended pH operating range
• MS and shield selectivities
• Good peak shapes for basic compounds
• Proven platform for established HPLC methods

Additional Information

XTerra is part of the first generation of Waters Hybrid Particle Technology. The organic-inorganic particle matrix is more resistant to alkaline hydrolysis than conventional silica and therefore allows for an expanded pH operating range. In addition to classic RP18 and RP8 phases, the series offers MS variants with low column bleed as well as Shield phases with embedded polar groups. XTerra is particularly relevant for existing methods where the original hybrid selectivity and historical method compatibility must be maintained.

Legal Information

XTerra is a registered trademark of Waters Corporation, Milford, Massachusetts, USA.