Acquity® UPLC BEH C18 Column, 130Å, 1.7 µm, 2.1 mm X 50 mm, 1/pkg

The Waters ACQUITY UPLC BEH C18 UPLC column 50x2.1mm, 1.7µm, is based on an octadecylsilyl phase (other designations: ODS, RP-18, C18) on ethylene-bridged-hybrid (BEH) particles and is used in reversed-phase chromatography. The BEH hybrid matrix combines high mechanical stability (1240 bar) with a broad pH working range (1.0-12.0) and very good peak shape. The Waters ACQUITY UPLC BEH C18 offers C18 selectivity for hydrophobic, neutral, acidic and basic analytes and can be used in isocratic or gradient-based methods. The high pH stability allows bases to be analysed in the neutral state. Typical applications of the Waters ACQUITY UPLC BEH C18 are generic RP methods, pharmaceutical active ingredients, impurity profiles, LC–MS analysis and method development.

Features and Benefits

• UHPLC particles
• BEH, CSH, and HSS particle technologies for broad selectivity
• High reproducibility
• Wide range of phases for method development and routine analysis
• Suitable for pharmaceutical, biopharmaceutical, environmental, food, and research applications

Additional Information

The Waters ACQUITY series includes sub-2-µm UPLC phases based on hybrid particles, high-strength silica, and charged-surface hybrid materials. BEH particles consist of an organic-inorganic hybrid matrix and offer high chemical and mechanical stability. HSS particles provide silica-like selectivity with high pressure stability, while CSH particles enable particularly good peak shapes for basic analytes in LC-MS-friendly mobile phases thanks to a controlled surface charge. Compatible VanGuard or Guard systems protect the main column from matrix components.

Legal Notices

ACQUITY is a registered trademark of Waters Corporation, Milford, Massachusetts, USA.