LiChroCART 75x10mm Aluspher 100 Å RP-Select B 5µm HPLC Cartridge Column

The Aluspher 100 RP-select B HPLC column 75x10mm, 5µm, is based on spherical aluminium oxide with a polybutadiene coating and a pore size of approximately 100 Å. The alkali-resistant reversed-phase allows mobile phases in the range of approximately pH 2 to 12 and thus particularly supports the non‑ionised retention of basic analytes. Aluspher 100 RP-select B is used for basic active pharmaceutical ingredients, alkaloids as well as neutral and acidic compounds when symmetrical peaks under basic elution conditions are required.

Features and Benefits

• Spherical aluminum oxide particles
• Unmodified polar and alkali-resistant reverse-phase columns available
• Intrinsic selectivity for neutral, basic, and acidic compounds
• RP-select-B version for use with basic eluents

Additional Notes

Aluspher is based on spherical aluminum oxide and thus differs fundamentally from conventional silica phases. The amphoteric metal oxide surface and the polybutadiene coating of the RP-select-B phase generate unique retention mechanisms. When transferring the method, the eluent composition, water content, pH, and conditioning must be specifically adapted to the respective modification.

Legal Information

Aluspher is a registered trademark of Merck KGaA, Darmstadt, Germany.