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LiChroCART 55x3.0mm ChiraDex 100 Å β-cyclodextrin 5µm HPLC Cartridge Column
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Product Description
The ChiraDex HPLC column 55x3.0mm, 5µm, contains beta-cyclodextrin covalently bonded to spherical 100 Å silica particles. Enantiomers are separated by differently stable inclusion complexes in the hydrophobic cyclodextrin cavity as well as by stereoselective hydrogen bonding. ChiraDex exhibits broad enantioselectivity and is used, among other things, for chiral hydrocarbons, steroids, phenol esters, aromatic amines and five- to seven-membered heterocycles.
Features and Benefits
- Covalently bound beta-cyclodextrin selectors
- Broad enantioselectivity
- Chiral recognition via inclusion complexes and stereoselective hydrogen bonds
- Can be used with simple reverse-phase eluents in many cases
- High-resolution version available for higher separation performance
Additional Notes
ChiraDex utilizes the hydrophobic cavity and hydrophilic openings of beta-cyclodextrin to form diastereomeric inclusion complexes. Enantioselectivity depends on molecular size, substitution pattern, pH, organic content, and temperature. The silica-based material is typically operated within a pH range of approximately 3 to 7.5.
Legal Information
ChiraDex is a registered trademark of Merck KGaA, Darmstadt, Germany.
Product Specification
| Brand | ChiraDex |
|---|---|
| Product Type | HPLC Cartridge Column |
| Length | 55 mm |
| Internal Diameter | 3.0 mm |
| Particle Size | 5 µm |
| Chemistry | Chiral |
| Chemistry Producers Term | β-cyclodextrin |
| Pore Size | 100 Å |
| Bet Surface Area [m2/g] | 300.0 |
| Country of Origin | Germany |
| Column Type | Analytical Column |
| Base Material | β-cyclodextrin |
| Hardware Type | LiChroCART |
| pH Minimum | 3.0 |
| pH Maximum | 7.5 |
| Mode of Separation | Chiral Chromatography |
| Technology | HPLC |
| Matrix | Silica |
| Particle Morphology | spherical, fully porous |
| Pressure Stability | 190 bar |
