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The Merck ChiraDex guard cartridges 4x4.0mm, 5µm, are used to protect ChiraDex HPLC columns. LiChroCART guard cartridges can be operated together with the matching manu-CART holder 1.51486.0001 upstream of the analytical cartridge column.
ChiraDex utilizes the hydrophobic cavity and hydrophilic openings of beta-cyclodextrin to form diastereomeric inclusion complexes. Enantioselectivity depends on molecular size, substitution pattern, pH, organic content, and temperature. The silica-based material is typically operated within a pH range of approximately 3 to 7.5.
ChiraDex is a registered trademark of Merck KGaA, Darmstadt, Germany.
| Brand | ChiraDex |
|---|---|
| Product Type | HPLC Guard Cartridges |
| Length | 4 mm |
| Internal Diameter | 4.0 mm |
| Particle Size | 5 µm |
| Chemistry | Chiral |
| Chemistry Producers Term | β-cyclodextrin |
| Pore Size | 100 Å |
| Bet Surface Area [m2/g] | 300.0 |
| Country of Origin | Germany |
| Base Material | β-cyclodextrin |
| Hardware Type | LiChroCART |
| pH Minimum | 3.0 |
| pH Maximum | 7.5 |
| Mode of Separation | Chiral Chromatography |
| Technology | HPLC |
| Matrix | Silica |
| Particle Morphology | spherical, fully porous |
| Pressure Stability | 190 bar |