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The Astec CHIROBIOTIC TAG HPLC column 250x21.2mm, 5µm, is based on teicoplanin aglycon as a chiral selector. The Astec CHIROBIOTIC TAG contains no sugar residues of teicoplanin and therefore shows a different balance of steric and polar recognition. The Astec CHIROBIOTIC TAG is used for chiral actives, amino acid derivatives, polar bases and screening strategies where CHIROBIOTIC T is not optimally selective.
Astec CHIROBIOTIC columns are based on macrocyclic glycopeptide selectors bound to high-purity silica. The selectors offer multiple interaction sites, including ionic interactions, hydrogen bonds, dipole interactions, steric recognition, and hydrophobic contributions. As a result, CHIROBIOTIC phases can be used in normal-phase, reverse-phase, polar-organic, and polar-ionic modes. The choice of selector determines which enantiomers are recognized particularly well.
CHIROBIOTIC is a registered trademark of the manufacturer Merck KGaA, Darmstadt, Germany.
| Brand | Astec Chirobiotic |
|---|---|
| Product Type | HPLC Column |
| Length | 250 mm |
| Internal Diameter | 21.2 mm |
| Particle Size | 5 µm |
| Chemistry | Chiral |
| Chemistry Producers Term | Chirobiotic TAG |
| Pore Size | 100 Å |
| Country of Origin | Germany |
| Column Type | Preparative Column |
| Base Material | Teicoplanin Aglycon |
| Hardware Material | Stainless Steel |
| Hardware Type | Ready-to-use Column |
| pH Minimum | 3.0 |
| pH Maximum | 6.8 |
| Temperature Maximum [°C] | 45 |
| Mode of Separation | Chiral Chromatography |
| Technology | HPLC |
| Matrix | Silica |
| Particle Morphology | spherical, fully porous |
| Pressure Stability | 241 bar |