Astec® Chirobiotic® R Chiral HPLC Column, 5 µm particle size, L x I.D. 15 cm x 2.1 mm

The Astec CHIROBIOTIC R HPLC column 150x2.1mm, 5µm, utilises ristocetin A as a macrocyclic glycopeptide selector. The Astec CHIROBIOTIC R provides a different chiral recognition compared with vancomycin or teicoplanin phases and thus expands the screening window. Typical areas of use for the Astec CHIROBIOTIC R are pharmaceutical active substances, ionic enantiomers, amino alcohols and classes of compounds that are not adequately separated on other CHIROBIOTIC phases.

Features and Benefits

• Macrocyclic glycopeptide CSPs
• Multiple chiral separation modes possible
• Suitable for ionic and polar enantiomers
• High selectivity for amino acids and active ingredients
• Complementary phases for screening

Additional Information

Astec CHIROBIOTIC columns are based on macrocyclic glycopeptide selectors bound to high-purity silica. The selectors offer multiple interaction sites, including ionic interactions, hydrogen bonds, dipole interactions, steric recognition, and hydrophobic contributions. As a result, CHIROBIOTIC phases can be used in normal-phase, reverse-phase, polar-organic, and polar-ionic modes. The choice of selector determines which enantiomers are recognized particularly well.

Legal Information

CHIROBIOTIC is a registered trademark of the manufacturer Merck KGaA, Darmstadt, Germany.