Astec® Chirobiotic® V Chiral HPLC Column, 5 µm particle size, L x I.D. 25 cm x 4.6 mm

The Astec CHIROBIOTIC V HPLC column 250x4.6mm, 5µm, is based on vancomycin as a macrocyclic glycopeptide selector on silica. The Astec CHIROBIOTIC V is used for chiral HPLC separations in which ionic and polar interactions play an important role. Typical applications of the Astec CHIROBIOTIC V are amino acids, amines, acidic active substances, zwitterionic substances and pharmaceutical enantiomeric purity.

Features and Benefits

• Macrocyclic glycopeptide CSPs
• Multiple chiral separation modes possible
• Suitable for ionic and polar enantiomers
• High selectivity for amino acids and active ingredients
• Complementary phases for screening

Additional Information

Astec CHIROBIOTIC columns are based on macrocyclic glycopeptide selectors bound to high-purity silica. The selectors offer multiple interaction sites, including ionic interactions, hydrogen bonds, dipole interactions, steric recognition, and hydrophobic contributions. As a result, CHIROBIOTIC phases can be used in normal-phase, reverse-phase, polar-organic, and polar-ionic modes. The choice of selector determines which enantiomers are recognized particularly well.

Legal Information

CHIROBIOTIC is a registered trademark of the manufacturer Merck KGaA, Darmstadt, Germany.