Acclaim AmG C18 3µm 4.6x150mm

The Acclaim AmG C18 HPLC column 150x4.6mm, 3µm, based on high-purity silica with a specially deactivated C18 surface. The reversed phase was developed for highly polar, multiply basic aminoglycosides and suitable ion-pair or derivatisation-based methods. Controlled silanol activity improves peak shape and recovery for this challenging drug class. Acclaim AmG C18 is used particularly for aminoglycoside antibiotics in pharmaceutical and biological samples.

Features and Benefits

• Selectivities for RP, HILIC, mixed-mode, and SEC
• Phases for general and application-specific LC methods
• Silica and polymer materials
• Analytical, UHPLC, and semipreparative formats

Additional Notes

The Acclaim product family includes classic reverse-phase, polar embedded, and HILIC phases, multimodal materials, and application-optimized columns for ions, surfactants, explosives, carbonyls, carbamates, and organic acids. The selection depends on the analyte’s polarity, charge state, desired retention mechanism, and detection method. For mixed-mode columns, the pH value, buffer type, ionic strength, and organic content must be optimized together; SEC ranges are always calibration-dependent reference values.

Legal Information

Thermo Scientific is a brand name of Thermo Fisher Scientific Inc. Acclaim refers to a product line within the Thermo Scientific chromatography portfolio.