Acclaim 120 C8 3µm 3X150mm

The Acclaim 120 C8 HPLC column 150x3.0mm, 3µm, consists of high-purity 120Å silica with an endcapped C8 phase (other designations: RP-8, C8) for use. The shorter alkyl chain produces lower hydrophobic retention in reversed-phase chromatography than C18. This allows run times to be shortened and highly hydrophobic samples to be examined with milder eluents. Acclaim 120 C8 is used particularly for pharmaceutical compounds, metabolites, peptides and medium-polarity organic compounds.

Features and Benefits

• Selectivities for RP, HILIC, mixed-mode, and SEC
• Phases for general and application-specific LC methods
• Silica and polymer materials
• Analytical, UHPLC, and semipreparative formats

Additional Notes

The Acclaim product family includes classic reverse-phase, polar embedded, and HILIC phases, multimodal materials, and application-optimized columns for ions, surfactants, explosives, carbonyls, carbamates, and organic acids. The selection depends on the analyte’s polarity, charge state, desired retention mechanism, and detection method. For mixed-mode columns, the pH value, buffer type, ionic strength, and organic content must be optimized together; SEC ranges are always calibration-dependent reference values.

Legal Information

Thermo Scientific is a brand name of Thermo Fisher Scientific Inc. Acclaim refers to a product line within the Thermo Scientific chromatography portfolio.