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Advanced Materials Technology - AMT
FusedCore® particle technology for fast and super-rugged HPLC-columns
Advanced Materials Technology™ is genuine developer and producer of packing materials with FusedCore® technology, bridging the gap between UHPLC and HPLC. The company Advanced Materials Technology has been created by outstanding pioneers from the field of high-performace liquid chromatography. These individuals have been responsible in the past for the invention, manufacture and product launch of Zorbax® brand columns and later founded Rockland Technologies. With their 30-plus years of experience in the chromatography world they created a new company dedicated to new innovative HPLC products.
The introduction of HALO® 2.7 micron Fused-Core® columns in the year 2006 has revolutionised the chromatography world. HALO® columns deliver outstanding separation power (theoretical plates) comparable to UHPLC columns without the back pressure seen in sub 2 micron columns. HALO® bridges the gap between UHPLC and HPLC. AMT give customer webinars on demand, please contact us for further information!
% Special offer %
In 2025, Advanced Materials Technology celebrates the 20th anniversary of the company. MZ-Analysentechnik has been the exclusive sales partner for Germany since the very beginning. We are celebrating AMT's anniversary with a special promotion. From now until 30 June 2025, you will receive a 20% discount on the entire HALO range.
![[English:]](https://cms.mz-at.de/fileadmin/_processed_/6/c/csm_offer_halo_elevate-c18_40pc_630x178px_f24927a43c.webp "[English:]")
Technical Data
Milestones of AMT
Learn how HALO® columns are manufactured and how quality is considered in the process from the very beginning.
What are the advantages of fused-core technology?
In fused-core technology (or core-shell, superficially porous particles SPP), the particles consist of a non-porous core and a porous shell. This thin, porous shell enables faster mass transfer of the analytes between the mobile and stationary phases. This reduces the broadening of peaks due to mass transfer and therefore the B term of the van Deemter equation is smaller compared to fully porous particles. With fused-core technology, more uniform particles are also obtained, resulting in a more uniform flow through the packing bed. This in turn reduces the A-term of the van Deemter equation.
The reduction in the A-term and B-term results in significantly lower theoretical plate heights and therefore higher efficiencies (higher plate counts) of core-shell particles. This means that higher flow rates are possible with the same efficiency. Thus, a 2.7µm particle with fused-core technology has a similar separation performance as a sub 2µm fully porous material. Due to the non-porous core, the back pressure is as low as with 5µm particles, so that a UHPLC-like performance can be achieved on a conventional HPLC.
Which product line can be used when?
- HALOCore-shell material with small pores for fast separations
- HALO Peptides: Core-shell material with 160Ã… for peptide analysis
- HALO Protein: Core-shell material with 400 and 1000Ã… for proteins and antibodies
- HALO OLIGO C18: Core-shell material with 120Ã… for oligonucleotides with up to 60 bases
- HALO Elevate C18: Core-shell hybrid-material with modified surface for higher pH stability
- HALO PCS: Core-shell material with special, positivly carged surface for basic compounds
- HALO PFAS: Core-shell material specially optimised for PFAS
- HALO INERT: Inert HPLC hardware that minimises unwanted interactions
- HALO LPH-C18: Core-shell material with increased stability at low pH
- HALO PAH: Core-shell material specially optimised for PAH
- HALO Glycan: Special core-shell material for the analysis of oligosaccharides and glycopeptides
- HALO Column Kits: Kits with three columns each for simplified method development
Downloads
Brochures
AMT DANDY VICE Instructions-for-use Brochure
AMT HALO 1.5mm Column Fused Core UHPLC Columns Brochure
AMT HALO 2 ES C18 Peptide Column Brochure
AMT HALO 5 Fused Core HPLC Columns Brochure
AMT HALO® C18 Isocratic Separation on Aflatoxins Brochure
AMT HALO C30 Columns Brochure
AMT HALO Elevate C18 Brochure
AMT HALO OLIGO C18 Brochure
AMT HALO PCS-C18 Brochure
AMT HALO® PCS-Family HPLC Brochure
AMT HALO 90Ã… C18, AQ-C18, Biphenyl, New Alternatives to C18 Brochure
AMT Enhanced Selectivity With the HALO 160Ã… Phenyl-Hexyl Column Brochure
AMT HALO Bioclass Protein 400Ã… Diphenyl Brochure
AMT HALO 1000Ã… C4 Protein Column for High Resolution Separation of a Monoclonal Antibody
AMT HALO 1000Ã… Diphenyl Brochure
AMT HALO® 1000Å Diphenyl Brochure
AMT HALO® Applications Collection Brochure
AMT HALO AQ-C18 Columns Brochure
AMT HALO Bioclass 1000Ã… Protein Selectivity Kit Biotherapeutic Method Development Guide
AMT HALO Bioclass Fused-Core Columns Brochure 2018
AMT HALO Bioclass Brochure
AMT HALO Biphenyl Brochure
AMT HALO® Catalog
AMT HALO® Catalog 2023
AMT HALO Introducing HALO PFAS Column Solutions
AMT HALO Enviroclass - HALO-PFAS Environmental Analysis
AMT HALO Peptide ES-C18 UHPLC Columns Separation of Peptides Brochure
AMT HALO Fused-Core Technology Brochure
AMT HALO Fused-Core HPLC Columns Product Bulletin Brochure
AMT HALO2 FusedCore columns
AMT, HALO, LPH - C18 Columns
AMT HALO Method Development Kit Promotion Brochure
AMT HALO Introducing HALO PAH Columns Brochure
AMT HALO PFAS PAH Pesticides Enviromental Analysis Brochure
AMT HALO PFP UHPLC Columns Brochure
AMT HALO Phenyl Hexyl UHPLC Columns Brochure
AMT HALO RP Amide C8 C18 UHPLC Columns Alternate Complementary Selectivity Brochure
Applications
AMT HALO 1.5mm Column 90Ã… C18 Sensitivity Solvent Savings with Cannabinoids Application
AMT HALO 1.5mm-Column 90Ã… C18 Alkylphenones Application
AMT HALO 1.5mm Column 90Ã… C18 Small Molecule Cough And Cold Meds Application
AMT HALO 1.5mm Column 160Ã… ES C18 Trastuzumab Tryptic Digest Application
AMT HALO 1.5mm Column 1000Ã… Diphenyl Intact Trastuzumab Application
AMT HALO 1.5mm Column 1000Ã… Diphenyl Reduced Trastuzumab Application
AMT HALO 1.5mm Column 1000Ã… C4 Sensitivity Increase of Mixed Proteins Application
AMT HALO Fast Peptide Separation with HALO 2 Peptide ES-C18 Application
AMT HALO 2 ES C18 Peptide High Temperature Low pH Stability Application
AMT HALO 2 ES C18 Peptide Peak Capacity Application
AMT HALO 5 C18 Determination of Caffeine in Soda Application
AMT HALO 90Ã… Biphenyl LC MS Separation of Fentanyl & Analogues in Synthetic Urine Application
AMT Fast Separation of Ten Cannabinoids on HALO C18
AMT Separation of 14 Cannabinoids on HALO C18
AMT Isocratic Separation of 18 Cannabinoids
AMT HALO Glycan Separation of Amino Acids by HILIC/MS
AMT HALO Glycan Analysis of Underivatized Essential Amino Acids by HILIC/MS
AMT HALO 90Ã… LPH C18 Pesticide Screening of Barley Application
AMT HALO AQ-C18 & HALO Penta-HILIC Amino Acid Analysis in Biological Matrices
AMT HALO C18 2.7um Separation of 6 Flavonoids Application
AMT HALO C18 HPLC Analysis of Chlorogenic Acid in Coffee Extract Application
AMT HALO C18 Separation of Steroid Hormones & Hormone Conjugates Application
AMT HALO Elevate C18 Amitriptyline Stability Test Applications
AMT HALO Elevate C18 Nicotine Analysis Application
AMT HALO Elevate C18 Omeprazole Analysis Application
AMT HALO Elevate C18 Separation of Antidepressants Applications
AMT-HALO® Separation of Procainamide-Labeled Dextran Standards
AMT-HALO® Separation of PNGase-Released & Labeled N-Glycans
AMT Advantages of HALO OLIGO C18
AMT HALO OLIGO C18 Separation of Oligonucleotide Ladder via LC/MS
AMT HALO OLIGO C18 Oligonucleotide Performance Mix
AMT HALO OLIGO C18 Oligonucleotide Ladder via UV Detection
AMT HALO OLIGO C18 Lot-to-Lot Reproducibility
AMT HALO PFAS EPA Method 1633 for PFAS
AMT HALO Comparison on 1000Ã… C4, ES-C18, Diphenyl
AMT-HALO® Analysis of PFAS in Well Water Spiked with Standards
AMT HALO Analysis of PFAS in Well Water Spiked with Standards Application
AMT HALO Analysis of proteins
AMT HALO Pain Management Panel Comparison on HALO Biphenyl and C18
AMT HALO C18 Separation of Neonicotinoids
AMT-HALO® Demonstration of the HALO® PFAS Delay Column
AMT HALO Food & Beverage LC-MS Separation of Common Catechins Found in Tea
AMT HALO Pharmaceuticals Low pH Stability with HALO LPH-C18 Columns
AMT HALO® PAH App-Note_18-PAH-HALO®, PAH-3x100
AMT HALO® PAH App-Note EPA 610-2-under-5min
AMT HALO® App-Note PAH-vs-FPP
AMT HALO Penta-HILIC Separation of Nucleotides
AMT-HALO® PFAS Analysis According to EPA 533
AMT-HALO® PFAS Analysis According to EPA 537.1 Using HALO® 90 Å C18, 2.0 μm
AMT-HALO® PFAS Analysis According to EPA 537.1
AMT-HALO® PFAS Analysis According to EPA 8327
AMT HALO Environmental PFAS Analysis According to EPA 533 Application
AMT HALO PFAS Analysis According to EPA 537.1 Application
AMT HALO PFAS Analysis According to EPA 8327 Application
AMT HALO Phenyl Hexyl & RP Amide Phases Separation of Food Additives Application
AMT HALO Phenyl Hexyl Separation Of Penicillins Application
AMT-HALO® Rapid Analysis of 33 PFAS Compounds in Under 5 Minutes
AMT-HALO® Rapid PFAS Analysis According to EPA 537.1 using HALO® 90 Å Phenyl-Hexyl, 2.7 μm Peak
AMT HALO RP Amide Separation of Amoxicillin & Ampicillin Application
AMT HALO Separation of 18 Cannabinoids Using HALO LPH-C18 Application
AMT HALO® Separation-of-Aflatoxins
AMT HALO Separation of Anthocyanins in Blueberries Application
AMT HALO Separation of Common Catechins & Caffeine Found in Tea via LC-UV Application
AMT HALO Separation of Polyphenols in Wine Application
AMT HALO MZ-Apps HALO-Glycan Information Sheet
AMT HALO 2 MZ-Apps Peptides & Proteins ES-C18 Lot Reproducibility Application
AMT HALO MZ-Apps Rp HALO 400Ã… C4 Protein Columns
AMT HALO MZ-Apps Rp HALO 1000Ã… Brochure
AMT HALO MZ-Apps Rp Halo 1000Ã… C4 High Resolution Separation of a Monoclonal Antibody Application
AMT HALO MZ-Apps Rapid Separation of Vitamin E Congeners on HALO PFP Application
AMT HALO MZ-Apps Separation Of Water Soluble Vitamins Application
Technical Support
AMT HALO 1.5mm Column 90Ã… C18 Microflow Extracolumn Dispersion Technical Support
AMT HALO 1.5mm Column 160Ã… ES C18 1000Ã… Diphenyl Top-Down & Bottom-Up Technical Support
AMT HALO C30 Columns Technical Support
AMT HALO Rapid & High Resolution Fused-Core Solutions for PFAS Analysis
AMT HALO Bioanalysis Solutions Guidebook
AMT HALO Cannabinoid Separations and the Impact of LC Column Selectivity
AMT HALO Method Conversion Guidebook
AMT HALO®-PAH Small-Molecule
AMT HALO Toss-Sheet on High Resolution Separation of 18 PAH Compounds
AMT HALO PFAS, 2.7 μm Column Care & Use Sheet Application
AMT HALO PFAS Delay, 2.7 μm Column Care & Use Sheet
AMT-HALO PFAS in Bottled Water Technical Support
AMT HALO RP Chemistries Utilizing Selectivity for HPLC Separations Technical Support
The right column for you - we will be happy to support you individually
Competent consultants are always at your side. Write a message to our consultants, we will get back to you and give you individual support.
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Certificates of analysis, MSDS, data sheets