Kromasil EternityXT-5-C8 20 x 50 mm

The Kromasil Eternity XT C8 HPLC/UHPLC column 50x20mm, 5µm, is based on an octyl phase (other designations: RP-8, C8) on the reinforced EternityXT platform. The C8 modification offers a moderately less hydrophobic retention than C18 and can therefore shorten run times or change selectivity. Kromasil Eternity XT C8 is particularly suited for fast reversed-phase separations of peptides, medium-polar to hydrophobic compounds and methods where C18 is too strongly retentive. Typical applications are peptide analysis, pharmaceutical development, QC, method acceleration, UHPLC screening and scale-up of suitable HPLC methods.

Features and Benefits

• Reinforced EternityXT silica/organosilane surface for high chemical stability
• Particle sizes up to 1.8 µm for UHPLC, as well as larger particles for HPLC and scale-up
• Designed for fast reverse-phase separations and demanding pH conditions
• Good method transferability across different particle and column sizes
• Broad RP phase spectrum with C18, C8, and PhenylHexyl for flexible selectivity

Additional Information

Kromasil Eternity XT is based on the Eternity platform and utilizes a reinforced silica/organosilane backbone. This surface was developed to provide high chemical stability and a long stationary-phase lifespan under demanding reverse-phase conditions. With the availability of small particles down to 1.8 µm, Kromasil Eternity XT can be used for fast UHPLC methods; larger particle sizes support HPLC, method transfer, and scale-up. The uniform silica concept facilitates comparisons between C18, C8, and phenylhexyl selectivities. Matching Kromasil Eternity XT precolumn cartridges protect the main column and help reduce pressure spikes and performance decline caused by the sample matrix.

Legal Notices

Kromasil is a registered trademark of the manufacturer Nouryon, Bohus, Sweden.