Kromasil EternityXT-5-C18 20 x 250 mm

The Kromasil Eternity XT C18 HPLC-/UHPLC column 250x20mm, 5µm, is based on an octadecyl phase (other designations: ODS, RP-18, C18) on the reinforced EternityXT platform. The C18 modification combines strong hydrophobic retention with high chemical stability and is suitable for fast reversed-phase separations. Kromasil Eternity XT C18 can be used in UHPLC methods with small particles as well as in HPLC and scale-up methods with larger particles. Typical applications are pharmaceutical active substances, β-blockers, basic compounds, impurity analysis, QC methods, peptides and method optimisation under demanding RP conditions.

Features and Benefits

• Reinforced EternityXT silica/organosilane surface for high chemical stability
• Particle sizes up to 1.8 µm for UHPLC, as well as larger particles for HPLC and scale-up
• Designed for fast reverse-phase separations and demanding pH conditions
• Good method transferability across different particle and column sizes
• Broad RP phase spectrum with C18, C8, and PhenylHexyl for flexible selectivity

Additional Information

Kromasil Eternity XT is based on the Eternity platform and utilizes a reinforced silica/organosilane backbone. This surface was developed to provide high chemical stability and a long stationary-phase lifespan under demanding reverse-phase conditions. With the availability of small particles down to 1.8 µm, Kromasil Eternity XT can be used for fast UHPLC methods; larger particle sizes support HPLC, method transfer, and scale-up. The uniform silica concept facilitates comparisons between C18, C8, and phenylhexyl selectivities. Matching Kromasil Eternity XT precolumn cartridges protect the main column and help reduce pressure spikes and performance decline caused by the sample matrix.

Legal Notices

Kromasil is a registered trademark of the manufacturer Nouryon, Bohus, Sweden.