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The RNASep Semi-Prep Ultra High Capacity HPLC column 150x30mm is designed for exceptionally large RNA loads within the Semi-Prep series. RNASep Semi-Prep Ultra High Capacity employs an alkylated, non-porous PS/DVB matrix and offers up to 2 mg capacity. It is suitable for two-stage purifications, automated fraction collection and RNA for mRNA vaccines and other nucleic acid-based drug candidates.
The RNASep series is based on alkylated, non-porous polystyrene-divinylbenzene microspheres rather than a silica matrix. Short diffusion paths promote rapid mass transfer, while the hydrophobic alkylation, in combination with ion-pair buffers, enables RNA retention. Depending on the column format, RNASep ranges from purity testing to semi-prep purification. Typical applications include the separation of DNA, truncated or misfolded RNA species, and other impurities in mRNA and IVT workflows.
RNASep is a brand name of the manufacturer ADS Biotec Inc., Omaha, USA.
| Brand | RNASep |
|---|---|
| Product Type | HPLC Column |
| Length | 150 mm |
| Internal Diameter | 30 mm |
| Chemistry Producers Term | RNA |
| Pore Size | non-porous |
| Country of Origin | United States of America (USA) |
| Column Type | Preparative Column |
| Base Material | Styrene-divinylbenzene |
| Hardware Material | Stainless Steel |
| Hardware Type | Ready-to-use Column |
| Mode of Separation | Reversed Phase Chromatography (RP) |
| Technology | HPLC |
| Matrix | Polymer |