Waters Spherisorb OD/CN Cartridge 5µm 4.6 x 150mm, Box of 1

The Waters Spherisorb OD/CN HPLC column 150x4.6mm, 5µm, features a mixed octadecylsilyl/cyanopropyl modification (other designations of the C18 component: ODS, RP-18, C18). The alkyl groups provide hydrophobic retention while the cyano groups enable additional dipolar interactions. As a result Spherisorb OD/CN combines mixed-mode character with a reversed-phase selectivity that differs from pure ODS and CN phases. The endcapped phase is based on spherical 80Å silica, is classified as USP L10 and is used in the pH range from 2 to 8. Typical applications of the Waters Spherisorb OD/CN are selectivity screenings, separations of polar to moderately polar pharmaceuticals, structural isomers and existing methods that explicitly specify an OD/CN phase.

Features and Benefits

• Robust 80-Å silica
• Particle sizes of 3, 5, and 10 µm
• Phases for RP, NP, and ion exchange
• ODS1 and ODS2 with different ligand densities
• Analytical and preparative formats

Additional Information

The Spherisorb series is based on mechanically robust silica with a pore size of 80 Å and is available in several particle sizes. ODS1 has a lower ligand density and lower carbon loading, while ODS2 offers a more densely packed, end-capped C18 surface. The series is complemented by short alkyl chains, cyano, phenyl, amino, and silica phases, as well as strong anion- and cation-exchange phases. This allows for the coverage of a wide range of classical HPLC methods using a silica base that is consistent across the product family.

Legal Information

Spherisorb is a registered trademark of Waters Corporation, Milford, Massachusetts, USA.