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The PerfectSil Target C8 HD column 250x40mm, 5µm, is an octasilyl phase (also known as OS, RP-8, C8) with a high carbon loading for reversed-phase chromatography. This high surface loading makes it highly resistant to attack by bases. This extends the usable pH range to 2–11. Due to the high carbon loading, hydrophobic interactions are strongly pronounced. Compared to the PerfectSil Target ODS-3 HD, however, the PerfectSil Target C8 HD exhibits lower interactions with comparable selectivity. The still-strong hydrophobic interactions can be useful for highly lipophilic analytes. These columns can be used, for example, in pharmaceutical analysis, environmental analysis, food analysis, or pesticide and residue analysis.
The PerfectSil Target HD series is distinguished by its high pH stability. This pH stability is achieved through a high surface loading and a highly sophisticated end-capping process. To this end, the silica material is first pretreated to ensure that the modifications are evenly distributed across the entire surface. In addition to high pH stability, PerfectSil Target HD materials exhibit a very high carbon loading and good symmetry for basic compounds. The use of appropriate pre-column cartridges can extend the service life.
PerfectSil Target HD is a registered trademark of the manufacturer MZ-Analysentechnik GmbH, Mainz, Germany.
| Brand | PerfectSil Target HD |
|---|---|
| Product Type | HPLC Column |
| Length | 250 mm |
| Internal Diameter | 40 mm |
| Particle Size | 5 µm |
| Chemistry | C8 (RP-8, MOS, Octyl) |
| Chemistry Producers Term | C8 HD |
| Pore Size | 100 Å |
| USP Class | L7 |
| Carbon Load | 15.0 % |
| Bet Surface Area [m2/g] | 450.0 |
| Endcapping | endcapped |
| Country of Origin | Germany |
| Column Type | Preparative Column |
| Hardware Material | Stainless Steel |
| Hardware Type | Ready-to-use Column |
| pH Minimum | 2.0 |
| pH Maximum | 11.0 |
| Temperature Maximum [°C] | 60 |
| Mode of Separation | Reversed Phase Chromatography (RP) |
| Technology | HPLC |
| Matrix | Silica |
| Particle Morphology | spherical, fully porous |
| Pressure Stability | 400 bar |
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