ACE 5 UltraCore Method Development UHPLC/HPLC Kit 250x4.6mm (UltraCore SuperC18 and UltraCore SuperPhenylHexyl)

The Avantor ACE UltraCore SuperC18 HPLC-/UHPLC column 250x4.6mm, 5µm, combines solid-core particles with a proprietary octadecylsilyl modification (other designations: ODS, RP-18, C18) for reversed-phase chromatography. The Avantor ACE UltraCore SuperC18 offers high efficiency, low backpressure and extended pH stability for flexible method development. The C18 selectivity is suitable for fast gradients, LC-MS-compatible conditions and robust separations of basic and neutral analytes. Typical applications include pesticides, herbicides, vitamins, biomarker profiling, pharmaceutical assays and pH screening in method development.

Features and Benefits

• Silica-based solid-core and core-shell particles for high efficiency
• Fast separations at moderate backpressure
• Ultra-inert surface chemistry for reproducible peak shapes
• Extended-pH phases for robust method development
• Variants for small molecules as well as BIO phases for proteins and peptides

Additional Notes

The Avantor ACE UltraCore series uses spherical silica particles with a non-porous core and a porous outer layer. This solid-core architecture reduces diffusion paths and enables high separation efficiencies while maintaining low backpressure. The surface of the silica particles is designed to minimize unwanted silanol activity, which promotes symmetrical peaks and robust retention times. By using compatible UltraCore guard cartridges, the analytical column can be protected from matrix interference without altering the selective chemistry of the main column.

Legal Notices

Avantor ACE is a registered trademark of the manufacturer Avantor, Inc., Radnor, USA.