ACE Generix 5 C8, HPLC-Column 250 x 4.6mm

The Avantor ACE Generix C8 HPLC column 250x4.6mm, 5µm, has an octyl modification (other designations: RP-8, C8) on high-purity, fully porous silica for reversed-phase chromatography. The Avantor ACE Generix C8 exhibits lower hydrophobic retention than C18 and thereby enables shorter analysis times or milder elution conditions for strongly retained analytes. The C8 selectivity is particularly useful when classical C18 methods produce excessively long run times. Typical applications are routine HPLC, pharmaceutical monographs, organic impurities, moderately hydrophobic active substances, food analysis and method optimisation.

Features and Benefits

• High-purity, spherical, and fully base-deactivated silica
• Routine-oriented HPLC phases for validated methods and replacement columns
• Excellent efficiency and symmetrical peaks
• High reproducibility between columns and silica batches
• Individually tested columns with test chromatograms

Additional Information

Avantor ACE Generix is a robust HPLC series designed for routine analysis and cost-effective replacement methods. The base material is high-purity, spherical, fully porous silica with complete base deactivation, which supports reproducible peak shapes for acidic, basic, and neutral analytes. The series focuses on proven reverse-phase selectivities, making it particularly suitable for existing HPLC methods, quality control, and method transfer. Compatible Generix guard cartridges protect the silica matrix of the analytical column from matrix components and can extend the method’s lifespan.

Legal Notices

Avantor ACE is a registered trademark of the manufacturer Avantor, Inc., Radnor, USA.