ACE Oligo UHPLC Guards 2.1mm (3pk)

The Avantor ACE Excel Oligo guard cartridges 2.1mm, are used for column protection of Avantor ACE Excel Oligo HPLC and UHPLC columns with an internal diameter of 2.1mm. They serve to protect the oligonucleotide method from particulate contaminants and strongly adsorbing matrix components. For a reproducible ion-pair reversed-phase method the guard cartridge should be used with the same Oligo phase as the analytical column; the appropriate guard cartridge holder is holder H0011.

Features and Benefits

• Proprietary, encapsulated stationary phase for oligonucleotides
• Ion-pair reverse-phase chromatography compatible with LC-UV and LC-MS
• High pH stability for common oligonucleotide methods
• Ultra-inert, base-deactivated silica for reproducible peak shapes
• Low column bleed for sensitive MS detection

Additional Information

Avantor ACE Excel Oligo is based on an ultra-inert, base-deactivated silica backbone with proprietary stationary-phase encapsulation. This surface chemistry is designed to meet the high demands of oligonucleotide analysis, where pH stability, low column bleeding, and reproducible retention are critical. The material is designed for mobile phases and buffers used in ion-pair reverse-phase analysis of oligonucleotides. Appropriate guard cartridges protect the analytical oligo column from matrix interference without altering the selective chemistry of the main column.

Legal Notices

Avantor ACE is a registered trademark of the manufacturer Avantor, Inc., Radnor, USA.