ACE Excel 2 CN 100x4.6mm

The Avantor ACE Excel CN HPLC/UHPLC column 100x4.6mm, 2µm, is a cyano phase with a short alkyl spacer and can be used in both normal-phase and reversed-phase chromatography. The Avantor ACE Excel CN utilises dipole–dipole interactions and offers lower hydrophobicity than classical C18 phases. This yields alternative selectivities for polar molecules and compounds with double or triple bonds. The Excel format supports high efficiency and fast analyses on UHPLC and HPLC systems. Typical applications are nitroanilines, brompheniramine maleate, prontosil analogues, carbamic acid derivatives, methotrexate as well as methods where switching between normal phase and reversed phase is advantageous.

Features and Benefits

• UHPLC/HPLC hardware for high pressure stability and low system dispersion
• Ultra-inert, base-deactivated, fully porous silica particles
• Wide range of phases for rapid method development
• Excellent peak shape and reproducibility for acidic, basic, and neutral analytes
• Particle sizes for high resolution and fast routine analyses

Additional Information

Avantor ACE Excel combines ACE silica chemistry with a UHPLC-compatible column format. The high-purity, base-deactivated silica matrix minimizes secondary interactions and ensures reproducible retention times. The combination of inert silica, controlled ligand bonding, and pressure-stable hardware allows methods to be implemented in both UHPLC and conventional HPLC systems. Compatible Avantor ACE Excel guard cartridges protect the analytical column from the sample matrix and help maintain the performance of the Excel method over extended runs.

Legal Notices

Avantor ACE is a registered trademark of the manufacturer Avantor, Inc., Radnor, USA.