ACE 3 AQ Capillary Column 125*0.30mm

The Avantor ACE AQ HPLC column 125x0.3mm, 3µm, is a specially designed C18-type phase for reversed-phase chromatography with a very high water content in the mobile phase. The Avantor ACE AQ remains stably wettable under highly aqueous conditions and supports the retention of polar acids, bases and neutral compounds. Therefore the phase is suitable for early elution regions where classical C18 phases often show insufficient retention or wetting issues. Typical applications are organic acids, maleic and fumaric acid, paracetamol, cysteine, cystine, pharmaceutical impurities and polar environmental analytes.

Performance Characteristics and Benefits

• Ultra-inert, high-purity, base-deactivated silica particles
• Broad range of selectivity for reverse-phase, normal-phase, and HILIC applications
• Fully porous 100 Å and 300 Å phases for small molecules and biomolecules
• Excellent peak shapes for acidic, basic, and neutral analytes
• High reproducibility from column to column and batch to batch

Additional Information

The Avantor ACE Series is based on high-purity, spherical silica with very low metal contamination and targeted base deactivation. Controlled surface chemistry reduces the activity of free silanol groups, which promotes symmetrical peaks and reproducible retention times, particularly for basic analytes. The portfolio includes classic fully porous 100 Å phases, alternative selectivities, and 300 Å wide-pore materials for larger molecules. Using compatible Avantor ACE guard cartridges protects the silica backbone of the analytical column from matrix components and can extend the column’s service life.

Legal Notices

Avantor ACE is a registered trademark of the manufacturer Avantor, Inc., Radnor, USA.