Supelclean™ LC-4 SPE Tube, Wide Pore, bed wt. 500 mg, volume 3 mL, pk of 54

The Supelclean LC-4 Wide Pore SPE cartridge features a butyl modification (other designations: RP-4, C4) on a wide-pore silica. Due to the shorter alkyl chain and the pore structure that is more accessible to larger molecules, Supelclean LC-4 Wide Pore offers moderate hydrophobic retention while providing good accessibility for biomolecules. Supelclean LC-4 Wide Pore is used primarily for desalting, fractionation and sample preparation of peptides, proteins and other macromolecules.

Features and Benefits

• Wide selection of different SPE selectivities
• Silica, polymer, carbon, and adsorbent materials
• Solutions for extraction, enrichment, and matrix cleanup
• Single-bed, mixed-bed, and multilayer cartridges available
• For food, environmental, pharmaceutical, and bioanalytical applications

Additional Information

Supelclean does not refer to a single base matrix, but rather to a comprehensive family of SPE products with different retention mechanisms. Conventional LC phases are primarily based on fully porous silica and include reversed-phase, normal-phase, and ion-exchange modifications. The ENVI products complement acid-washed silica materials, cross-linked polymer adsorbents, and various carbon adsorbents. Alumina, Florisil, activated carbon, and zirconium-based materials expand the selection with distinct adsorption and matrix cleanup properties. Multilayer cartridges combine multiple sorbents in a defined sequence. Conditioning, sample pH, solvents, and elution conditions must therefore always be tailored to the specific Supelclean material and the target analytes.

Legal Information

Supelclean is a brand name of Sigma-Aldrich Co. LLC, St. Louis, USA, an affiliate of Merck KGaA, Darmstadt, Germany. ENVI-Carb and ENVI-WAX are also brand names of Merck KGaA or its affiliates. Florisil is a registered trademark of U.S. Silica Company, Frederick, USA.