Supelclean™ Hisep™ SPE Tube, bed wt. 500 mg, volume 3 mL

The Supelclean Hisep SPE cartridge has hydrophobic binding sites shielded by a hydrophilic external surface. Larger proteins are excluded from the porous retention zone, while smaller hydrophobic analytes can be retained with a retention strength similar to a C8 phase. Supelclean Hisep is therefore suitable for processing protein-rich samples when protein removal and extraction of low-molecular-weight organic compounds are to be combined in a single SPE step.

Features and Benefits

• Wide selection of different SPE selectivities
• Silica, polymer, carbon, and adsorbent materials
• Solutions for extraction, enrichment, and matrix cleanup
• Single-bed, mixed-bed, and multilayer cartridges available
• For food, environmental, pharmaceutical, and bioanalytical applications

Additional Information

Supelclean does not refer to a single base matrix, but rather to a comprehensive family of SPE products with different retention mechanisms. Conventional LC phases are primarily based on fully porous silica and include reversed-phase, normal-phase, and ion-exchange modifications. The ENVI products complement acid-washed silica materials, cross-linked polymer adsorbents, and various carbon adsorbents. Alumina, Florisil, activated carbon, and zirconium-based materials expand the selection with distinct adsorption and matrix cleanup properties. Multilayer cartridges combine multiple sorbents in a defined sequence. Conditioning, sample pH, solvents, and elution conditions must therefore always be tailored to the specific Supelclean material and the target analytes.

Legal Information

Supelclean is a brand name of Sigma-Aldrich Co. LLC, St. Louis, USA, an affiliate of Merck KGaA, Darmstadt, Germany. ENVI-Carb and ENVI-WAX are also brand names of Merck KGaA or its affiliates. Florisil is a registered trademark of U.S. Silica Company, Frederick, USA.