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The Supelclean LC-WCX SPE cartridge features carboxyl groups on a silica surface and functions as a weak cation exchanger. The ionisation of the functional groups in Supelclean LC-WCX can be controlled by pH, allowing basic analytes to be selectively retained and subsequently eluted under altered pH or ionic strength conditions. Supelclean LC-WCX is suitable for catecholamines, basic drugs, amines and other protonatable compounds.
Supelclean does not refer to a single base matrix, but rather to a comprehensive family of SPE products with different retention mechanisms. Conventional LC phases are primarily based on fully porous silica and include reversed-phase, normal-phase, and ion-exchange modifications. The ENVI products complement acid-washed silica materials, cross-linked polymer adsorbents, and various carbon adsorbents. Alumina, Florisil, activated carbon, and zirconium-based materials expand the selection with distinct adsorption and matrix cleanup properties. Multilayer cartridges combine multiple sorbents in a defined sequence. Conditioning, sample pH, solvents, and elution conditions must therefore always be tailored to the specific Supelclean material and the target analytes.
Supelclean is a brand name of Sigma-Aldrich Co. LLC, St. Louis, USA, an affiliate of Merck KGaA, Darmstadt, Germany. ENVI-Carb and ENVI-WAX are also brand names of Merck KGaA or its affiliates. Florisil is a registered trademark of U.S. Silica Company, Frederick, USA.
| Amount | 500 mg |
|---|---|
| Brand | Supelclean |
| Product Type | SPE Cartridges |
| Particle Size | 45 µm |
| Chemistry | Weak cation-exchange |
| Chemistry Producers Term | LC-WCX |
| Pore Size | 60 Å |
| Bet Surface Area [m2/g] | 475.0 |
| Country of Origin | Germany |
| Volume | 3 ml |
| Bed Mass [mg] | 500 mg |
| Mode of Separation | Ion Exchange Chromatography |
| Matrix | Silica |
| Particle Morphology | irregular, fully porous |