Discovery® HS C18 HPLC Column, 3 µm particle size, L x I.D. 5 cm x 4.6 mm

The Discovery HS C18 HPLC column 50x4.6mm, 3µm, is based on an octadecyl phase (other designations: ODS, RP-18, C18) on high-purity silica. The Discovery HS C18 is a modern reversed-phase with good peak shape for basic, acidic and neutral compounds. Typical applications of the Discovery HS C18 are active pharmaceutical ingredients, impurities, environmental analytes and QC methods.

Features and Benefits

• Wide range of selectivities
• Silica, zirconia, and Bio-Wide-Pore phases
• Suitable for RP, specialized RP, and bioanalytics
• Robust method development
• Compatible Supelguard column protection systems

Additional Information

The Discovery Series includes various material platforms and surface chemistries. In addition to classic silica-based reverse-phase columns, high-purity HS phases, pentafluorophenyl, RP-amide, and PEG selectivities, as well as zirconia-based phases, are available. Bio-Wide-Pore variants with larger pores are designed for peptides and proteins. This makes Discovery particularly well-suited for method development when standard C18 selectivity is insufficient or more robust surfaces are required.

Legal Information

Discovery is a registered trademark of the manufacturer Merck KGaA, Darmstadt, Germany.