Discovery® BIO Wide Pore C5 HPLC Column, 3 µm particle size, L x I.D. 5 cm x 4.6 mm

The Discovery BIO Wide Pore C5 HPLC column 50x4.6mm, 3µm, features a short-chain alkyl-modified surface with a large pore structure. The Discovery BIO Wide Pore C5 offers weaker hydrophobic retention than C8 or C18 and can therefore be advantageous for larger or highly hydrophobic proteins. Typical applications of the Discovery BIO Wide Pore C5 are intact proteins, protein variants, antibody fragments and fast bio-RP methods.

Features and Benefits

• Wide range of selectivities
• Silica, zirconia, and Bio-Wide-Pore phases
• Suitable for RP, specialized RP, and bioanalytics
• Robust method development
• Compatible Supelguard column protection systems

Additional Information

The Discovery Series includes various material platforms and surface chemistries. In addition to classic silica-based reverse-phase columns, high-purity HS phases, pentafluorophenyl, RP-amide, and PEG selectivities, as well as zirconia-based phases, are available. Bio-Wide-Pore variants with larger pores are designed for peptides and proteins. This makes Discovery particularly well-suited for method development when standard C18 selectivity is insufficient or more robust surfaces are required.

Legal Information

Discovery is a registered trademark of the manufacturer Merck KGaA, Darmstadt, Germany.