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The Astec CYCLOBOND II HPLC column 250x4.6mm, 5µm, based on native γ-cyclodextrin modification. The larger cavity of the Astec CYCLOBOND II can accommodate different molecular sizes than β-cyclodextrin phases.The Astec CYCLOBOND II is used for larger aromatic racemates, flexible molecules, natural products and chiral compounds where a larger inclusion geometry is advantageous.
Astec CYCLOBOND columns are based on β- or γ-cyclodextrin selectors bound to a silica backbone. The cyclodextrin cavity enables the formation of inclusion complexes, while hydroxy, acetyl, dimethyl, dinitrophenyl, or hydroxypropyl groups provide additional interactions. This allows for the differentiation of the shape, size, and functional groups of a pair of enantiomers. CYCLOBOND phases are used in chiral HPLC for screening, method development, and targeted enantiomer separations.
CYCLOBOND is a registered trademark of the manufacturer Merck KGaA, Darmstadt, Germany.
| Brand | Astec Cyclobond |
|---|---|
| Product Type | HPLC Column |
| Length | 250 mm |
| Internal Diameter | 4.6 mm |
| Particle Size | 5 µm |
| Chemistry | Chiral |
| Chemistry Producers Term | Cyclobond II |
| Pore Size | 100 Å |
| Country of Origin | Germany |
| Column Type | Analytical Column |
| Base Material | γ-cyclodextrin |
| Hardware Material | Stainless Steel |
| Hardware Type | Ready-to-use Column |
| pH Minimum | 3.5 |
| pH Maximum | 7.0 |
| Temperature Maximum [°C] | 50 |
| Mode of Separation | Chiral Chromatography |
| Technology | HPLC |
| Matrix | Silica |
| Particle Morphology | spherical, fully porous |
| Pressure Stability | 172 bar |