ToyoScreen CM-650M, 65 µm, 1000 Å 1ml * 6 columns

The miniaturised packing format of ToyoScreen GigaCap CM-650M contains TOYOPEARL GigaCap CM-650M with densely bound carboxymethyl groups. The chromatographic mode is weak cation exchange chromatography. High capacity is combined with pH-dependent selectivity. With ToyoScreen GigaCap CM-650M, binding, wash and elution conditions can be systematically compared for protein capture, mAb methods and comparison of strong and weak CEX media.

Features and Benefits

• Pre-packaged screening formats
• Manual and automated experiments
• 200 µL to 5 mL bed volume
• TOYOPEARL polymers
• Direct scale-up to process formats

Additional Information

ToyoScreen offers TOYOPEARL ion-exchange, mixed-mode, HIC, and affinity media in reproducibly pre-packed small formats. The classic 1- and 5-mL columns are suitable for manual or automated method development; RoboColumns enable parallel experiments in liquid-handling systems. This allows for the systematic investigation of binding, washing conditions, gradients, elution, and regeneration using identical resin chemistry. Since the same TOYOPEARL media are subsequently available as bulk process resin or in SkillPak columns, ToyoScreen results support scale-up from design space screening to the process column.

Legal Information

ToyoScreen is a registered trademark of Tosoh Corporation, Tokyo, Japan.