BioResolve Premier RP mAb Polyphenyl Column, 450 Å, 2.7 µm, 2.1 mm x 20 mm, 1/pk

The Waters BioResolve RP mAb Polyphenyl HPLC-/UHPLC column 20x2.1mm, 2.7µm, is based on solid-core particles and features a highly loaded polyphenyl modification. As a result, the Waters BioResolve RP mAb Polyphenyl is used in reversed-phase chromatography. The polyphenyl surface is designed for intact mAbs, ADCs and IdeS fragments and reduces carryover while providing good peak capacity. Typical applications of the Waters BioResolve RP mAb Polyphenyl are mAb subunit analysis, antibody–drug conjugates, intact protein characterisation and biopharmaceutical LC–MS.

Features and Benefits

• Biopharma-specific RP, IEX, SEC, and affinity chromatography for mAb analysis
• High batch-to-batch consistency through controlled particle and packing production
• Wide range of selectivities for method development and routine analysis
• Suitable for biopharmaceutical applications

Additional Information

The Waters BioResolve series addresses specific biopharmaceutical separation challenges. Depending on the phase, solid-core particles, nonporous polymeric ion exchangers, SEC materials, or Protein A affinity surfaces are used. The materials are tailored to mAb, protein, and biotherapeutic workflows and are often combined with compatible standards, buffers, and low-adsorption hardware.

Legal Notices

BioResolve is a registered trademark of Waters Corporation, Milford, Massachusetts, USA.