XSelect HSS Cyano (CN) Intelligent Speed (IS) Column, 100Å, 5 µm, 4.6 mm X 20 mm, 1/pkg

The Waters XSelect HSS Cyano HPLC/UHPLC column 20x4.6mm, 5µm, is based on High-Strength-Silica particles and features a cyanopropyl modification. The Waters XSelect HSS Cyano is intended for use in normal-phase and reversed-phase chromatography. The cyano group generates low hydrophobicity and pronounced dipolar interactions. Typical applications of the Waters XSelect HSS Cyano include more polar small molecules, normal-phase methods, alternative RP selectivity and method development.

Features and Benefits

• CSH and HSS particle platforms
• Wide selectivity range for method development
• Good peak shapes for basic analytes
• High retention on HSS phases
• Scalable between HPLC and UHPLC

Additional Notes

XSelect combines two deliberately different particle platforms. CSH uses a BEH hybrid framework with a controlled positive surface charge and is specifically designed to provide good peak shapes and increased loading capacity for basic compounds. HSS is based on high-strength silica and often provides stronger retention as well as different selectivities than BEH or CSH phases. C18, phenyl-hexyl, fluoro-phenyl, T3, PFP, and cyano offer a broad range of method development options; specialized peptide phases extend these concepts to bioanalytical separations.

Legal Information

XSelect is a registered trademark of Waters Corporation, Milford, Massachusetts, USA.