XBridge Peptide BEH C18 Column, 130Å, 10 µm, 4.6 mm X 250 mm, 1/pkg

The Waters XBridge BEH Peptide C18 HPLC/UHPLC column 250x4.6mm, 10µm, is based on an octadecylsilyl phase (also known as ODS, RP-18, C18) on BEH hybrid particles with a pore structure suitable for peptides. The Waters XBridge BEH Peptide C18 is designed for reversed-phase separations of hydrophilic and hydrophobic peptides at low or high pH. Typical applications are peptide mapping, peptide impurities and biopharmaceutical LC–MS methods.

Features and Benefits

• BEH hybrid particles for pH 1–12
• High temperature and pressure stability
• Particle sizes ranging from 2.5 to 10 µm
• Scalable from UHPLC to preparative chromatography
• Phases for small molecules and biomolecules

Additional Information

XBridge columns use ethylene-bridged hybrid particles in which organic bridges are incorporated into the inorganic backbone. This material architecture expands the usable pH range compared to conventional silica and enables robust methods even in the strongly alkaline range. The product family includes reverse-phase, shield, and phenyl-selective columns, as well as HILIC and amide-phase columns and wide-pore materials for peptides, proteins, glycans, and oligonucleotides. Identical chemistries across different particle sizes facilitate transfer between HPLC, UHPLC, and preparative formats.

Legal Information

XBridge is a registered trademark of Waters Corporation, Milford, Massachusetts, USA.